PRODUCT DETAILS

About Actinocin 0.5mg Injection

Dactinomycin is an anti-cancer medication. It works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication. Dactinomycin is used in the treatment of testicular cancer, Wilms' tumor, gestational trophoblastic neoplasia, and Ewing's sarcoma.

Uses of Actinocin 0.5mg Injection

Dactinomycin is used in the treatment of testicular cancer, Wilms' tumor, gestational trophoblastic neoplasia, and Ewing's sarcoma.

Medicinal Benefits of Actinocin 0.5mg Injection

Cancerous tumors are characterized by cell division, which is no longer controlled as it is in normal tissue. "Normal" cells stop dividing when they come into contact with like cells, a mechanism known as contact inhibition. Cancerous cells lose this ability. Cancer cells no longer have the normal checks and balances in place that control and limit cell division. The process of cell division, whether normal or cancerous cells, is through the cell cycle. The cell cycle goes from the resting phase, through active growing phases, and then to mitosis (division).

The ability of chemotherapy to kill cancer cells depends on its ability to halt cell division. Usually, the drugs work by damaging the RNA or DNA that tells the cell how to copy itself in the division. If the cells are unable to divide, they die. The faster the cells are dividing, the more likely it is that chemotherapy will kill the cells, causing the tumor to shrink. They also induce cell suicide (self-death or apoptosis).

Chemotherapy drugs that affect cells only when they are dividing are called cell-cycle specific. Chemotherapy drugs that affect cells when they are at rest are called cell-cycle non-specific. The scheduling of chemotherapy is set based on the type of cells, the rate at which they divide, and the time at which a given drug is likely to be effective. This is why chemotherapy is typically given in cycles.

Chemotherapy is most effective at killing cells that are rapidly dividing. Unfortunately, chemotherapy does not know the difference between cancerous cells and normal cells. The "normal" cells will grow back and be healthy but in the meantime, side effects occur. The "normal" cells most commonly affected by chemotherapy are the blood cells, the cells in the mouth, stomach, and bowel, and the hair follicles; resulting in low blood counts, mouth sores, nausea, diarrhea, and/or hair loss. Different drugs may affect different parts of the body.

Chemotherapy (anti-neoplastic drugs) is divided into five classes based on how they work to kill cancer. Although these drugs are divided into groups, there is some overlap among some of the specific drugs. The following are the types of chemotherapy:

Antitumor Antibiotics:
Antitumor antibiotics are made from natural products produced by species of the soil fungus Streptomyces. These drugs act during multiple phases of the cell cycle and are considered cell-cycle specific. There are several types of antitumor antibiotics, dactinomycin belongs to the chromomycin category.

Note: We strongly encourage you to talk with your health care professional about your specific medical condition and treatments. The information contained on this website is meant to be helpful and educational but is not a substitute for medical advice.

Directions for Use

• Dactinomycin is given as an injection into the vein under the supervision of a doctor only.
• Do not skip any dose and complete the course as suggested by your doctor.
• Use an effective method of birth control to avoid pregnancy while taking this medication.
• You may need to have blood tests to monitor your blood cells, platelet count, liver function, and kidney function during treatment.
• Inform your doctor immediately if you notice unusual bruising or bleeding or if you have dark, tarry, or bloody stools and dark urine.

Side Effects of Actinocin 0.5mg Injection

Nausea, Vomiting, Mouth ulcer, Loss of appetite, Glossitis (tongue inflammation), Lip inflammation, Diarrhea, Inflammation of the rectum, and Low blood platelets.

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.