PRODUCT DETAILS

About Dpressin Nasal Spray

DESMOPRESSIN is a hormone analog that belongs to the class of ‘antihemophilic agents’ primarily used to treat diabetes insipidus, post-hypophysectomy polyuria (extreme urination) polydipsia (extreme thirst), and bedwetting. Diabetes insipidus is a condition in which the body fails to control water balance, resulting in excessive urination. Hypophysectomy is the surgical removal of the hypophysis (pituitary gland).

DESMOPRESSIN contains Desmopressin, a human-made form (synthetic) of Vasopressin. Vasopressin is an antidiuretic (that controls fluid balance) hormone, synthesized in the pituitary gland's hypothalamus. When your body cannot produce enough vasopressin, DESMOPRESSIN is given to replace a low vasopressin level. It mimics the natural hormone, vasopressin and works by reabsorbing water from the kidneys, which controls excessive thirst and urination in diabetes insipidus. It also decreases the amount of urine produced and controls bedwetting in children. Being an anti-hemophilic agent, DESMOPRESSIN also reduces bleeding tendency in hemophilia (bleeding disorder) by promoting the release of blood clotting factors.

DESMOPRESSIN is available in the form of an oral tablet, sublingual tablet, injection, and nasal spray. Your doctor will decide the dosage depending on your medical condition. The common side effects of DESMOPRESSIN include headache, nausea, abdominal cramp, and flushing (a sense of warmth in the face, ears, neck, and trunk). Although not everyone experiences these side effects, if they occur, seek medical attention.

Before starting DESMOPRESSIN, let your doctor know if you have any medical history of severe kidney disease or hypernatremia (low sodium levels in your body), extreme thirst, uncontrolled high blood pressure, heart failure, and fluid retention. While using DESMOPRESSIN, limit water, and other fluids' intake since it may lead to electrolyte imbalance. Avoid drinking coffee, tea, cola, energy drinks, or other caffeine sources before bedtime, leading to increased urination. Pregnant and breastfeeding women should consult their doctor before using DESMOPRESSIN. Do not take or stop this medicine, if the doctor did not advise you to do so.

Uses of Dpressin Nasal Spray

Diabetes insipidus, Post-hypophysectomy polyuria (polydipsia), Bedwetting

Medicinal Benefits of Dpressin Nasal Spray

DESMOPRESSIN is a hormone analog that treats diabetes insipidus, post-hypophysectomy polyuria (extreme urination) or polydipsia (excessive thirst), and bedwetting. It contains Desmopressin, a synthetic form of Vasopressin (antidiuretic hormone), which mimics the natural hormone, vasopressin and works by limiting the amount of water eliminated in the urine, thus controlling excessive thirst and urination in diabetes insipidus. It also decreases the amount of urine produced, thereby preventing the urinary bladder from filling up at night time and controlling bedwetting in children. Being an anti-hemophilic agent, DESMOPRESSIN also reduces bleeding tendency in hemophilia (bleeding disorder) by promoting the release of blood clotting factors. 

Directions for Use

DESMOPRESSIN is available in the form of an oral tablet, sublingual tablet, injection, and nasal spray. Tablet: Swallow the tablet as a whole with a glass of water. Do not chew, bite, or break it. Please take it as prescribed by the doctor preferably with a meal. Nasal drops: Close one nostril by gently pressing on that side of your nose. Now, gently insert the spray bottle tip into the other nostril. Breathe in deeply through that nostril as you squeeze the bottle to release the medicated drops. Repeat the same in another nostril. Injection: DESMOPRESSIN is given as an intravenous (into a vein) injection by a doctor or nurse. Sublingual tablet: Place the tablet under the tongue or between the cheek and gum, and let it dissolve. Do not eat, drink, smoke, or use chewing tobacco while a tablet is dissolving.

Side Effects of Dpressin Nasal Spray

• Headache
• Nausea
• Abdominal cramp
• Flushing (sense of warmth in the face, ears, neck and trunk) 

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Before starting DESMOPRESSIN, let your doctor know if you have any medical history of severe kidney disease, hypernatremia (low sodium levels in your body), extreme thirst, uncontrolled high blood pressure, heart failure, fluid/mineral imbalance (cystic fibrosis), bleeding/clotting problems, and fluid retention. While using DESMOPRESSIN, limit water, and other fluids' intake since it may lead to electrolyte imbalance. Avoid drinking coffee, tea, cola, energy drinks, or other caffeine sources before bedtime, leading to increased urination. DESMOPRESSIN may contain sugars like lactose monohydrate. Inform your doctor if you have any allergic reactions or lactose intolerance before using DESMOPRESSIN. DESMOPRESSIN can cause pre-eclampsia, a serious complication in pregnant women. Pre-eclampsia can cause high blood pressure, edema (swelling due to the build-up of fluid), and proteinuria (protein in the urine) used by pregnant women. Please consult your doctor before starting DESMOPRESSIN if you are pregnant or planning to conceive. DESMOPRESSIN is excreted into breast milk when used by a breastfeeding mother. Please seek medical advice if you are a nursing mother before starting DESMOPRESSIN. Keep DESMOPRESSIN away from sunlight and refrigerate at temperatures between 2°C and 8°C. Do not keep DESMOPRESSIN in the freezer. 

Drug Interactions

Drug-Drug Interaction:

DESMOPRESSIN may interact with fit medicine (lamotrigine), antidepressants (escitalopram, fluoxetine, sertraline), and water pills (furosemide).

Drug-Disease Interaction:

 Tell your doctor before taking DESMOPRESSIN if you have a medical history of kidney disease, hypernatremia (low sodium levels in your body), severe thirst, uncontrolled high blood pressure, heart failure, fluid/mineral imbalance (cystic fibrosis), bleeding/clotting problems, and fluid retention. 

Safety Advice

ALCOHOL

It is unsafe to consume alcohol since it may worsen the side effects and increase urination.

PREGNANCY

DESMOPRESSIN is a pregnancy category B drug. It can cause pre-eclampsia in pregnant women leading to high blood pressure, edema (swelling due to the build-up of fluid), and proteinuria (protein in the urine). Please consult your doctor before starting DESMOPRESSIN if you are pregnant or planning to conceive.

BREAST FEEDING

DESMOPRESSIN is excreted into breast milk when used by a breastfeeding mother. Please seek medical advice before you start DESMOPRESSIN if you are nursing.

DRIVING

Do not drive or operate machinery if you experience any unmanageable side effects with DESMOPRESSIN.

LIVER

Please let your doctor know if you have any history of liver diseases or hepatic impairment when you are prescribed DESMOPRESSIN.

KIDNEY

DESMOPRESSIN is contraindicated in patients with moderate to severe renal impairment. Please let your doctor know if you have any history of kidney diseases when prescribed DESMOPRESSIN.