PRODUCT DETAILS

About Equisulin R Injection

INSULIN HUMAN is a hormone known as 'insulin' made in your pancreas, which helps your body utilize glucose (sugar) for energy. Human insulin is the name which describes synthetic insulin which is laboratory grown to mimic the insulin in humans. INSULIN HUMAN is a rapid-acting human insulin analogue for the treatment of diabetes mellitus in both children (above 2 years of age) and adults. When you have diabetes, your pancreas doesn’t make any insulin, enough insulin or the insulin it makes doesn’t work properly (called insulin resistance). And that’s why some people with diabetes are insulin-dependent, which means they need to take it as medication. Taking insulin helps you manage your blood sugar levels.

Uses of Equisulin R Injection

Type 1 Diabetes mellitus, Type 2 Diabetes mellitus

Medicinal Benefits of Equisulin R Injection

INSULIN HUMAN works by ensuring rapid and consistent sugar control. INSULIN HUMAN is a fast-acting form of insulin that helps lower blood sugar levels after the intake of food. Prevents the risk of having severe complications of diabetes. It stimulates the recovery of sugar in muscle and fat cells and thus suppresses the production of sugar in the liver. INSULIN HUMAN helps in improving the glycaemic control which in turn decreases the risk of progression of complications of diabetes like damage of retina (retinopathy), damage of kidney (nephropathy), damage of nerve cells (neuropathy), delayed wound healing, diabetic foot ulcer and others. Besides this, INSULIN HUMAN can be safely prescribed to the diabetic mother in the pregnancy as well as lactation stage.

Directions for Use

INSULIN HUMAN is administered 5-10 minutes before taking meal subcutaneously (SC) in the abdomen or thigh region. It can be also given intravenously (IV) with 0.9% sodium chloride infusion. However subcutaneous injection of INSULIN HUMAN in the abdomen region ensures faster absorption compared to other injection sites. INSULIN HUMAN is usually given once or twice daily when both rapid and prolonged effect of insulin is desired. In the initial requirement, the dose requirement is usually between 0.3 and 1.0 IU/kg per day. An injection of INSULIN HUMAN should be followed within 30 minutes by a meal or snack containing sugar/glucose (carbohydrates). If you are not well trained to self-administer INSULIN HUMAN, ask healthcare professional to administer it. Procedure for self-injecting insulin: • You should wash your hand first before injecting insulin. • Then roll the insulin bottle and wipe the bottle top. • Now pull the plunger of the syringe down to an appropriate number of units your doctor has prescribed. • Push the needle into the bottle and push syringe plunger down. • Now once again pull the plunger down to an appropriate number of units as prescribed by the doctor. • Pick the injection site and wipe it with an alcohol swab. Now, pinch up the skin and push the needle into the skin and then push the plunger in. • The needle should be kept under the skin for at least 6 seconds to make sure the entire dose is injected. • After injecting the insulin pull out the needle and dispose of the syringe safely. And then you can have a meal or snack.

Side Effects of Equisulin R Injection

Like all medicines, INSULIN HUMAN can cause side effects, although not everybody gets them. Common side effects of INSULIN HUMAN include hypokalaemia (low potassium), hypoglycaemia (low blood sugar level), local injection site reactions, lipodystrophy (fat deposition under the skin), rash, and pruritus (itchy skin). Severe hypoglycaemia can lead to unconsciousness and may result in temporary or permanent impairment of brain function or even death. It is not necessary for everyone to experience the above side effects. Please consult your doctor immediately if you experience worsening of any of the side-effects.

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

INSULIN HUMAN is for subcutaneous (under the skin) use only. However, some insulin form can be given intravenously (IV) with a saline solution of 0.9%. If you are changing the brand of insulin or if you need to inject your insulin by another method, it should be done under strict medical supervision. Cases of heart failure have been reported when pioglitazone was used with insulin, especially in patients who are at high risk of cardiac heart failure. The first symptoms of hyperglycaemia (high blood sugar level) may include symptoms like excessive thirst, dry mouth, increased frequency of urination, nausea, vomiting, drowsiness, flushed dry skin, loss of appetite and acetone odour of the breath. You should closely monitor these symptoms. Symptoms like heart failure, weight gain and oedema (fluid deposition in tissue) should not be overruled. It is advisable not to consume alcohol as it may either increase or decrease your blood glucose level. Care should be taken while travelling across more than two time zones. Your doctor may adjust your insulin schedule. INSULIN HUMAN may decrease the level of potassium, leading to a state of hypokalaemia that, if left untreated, may lead to respiratory paralysis, irregular heartbeat rhythm, coma and even death. Do not take INSULIN HUMAN if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription recreational drugs.

Drug Interactions

Drug-Drug Interaction:

INSULIN HUMAN may have an interaction with drugs including antidiabetic or blood sugar enhancing pills (glucagon, glipizide, metformin, sitagliptin, canagliflozin), blood pressure-lowering medicines (metoprolol, hydrochlorothiazide), bleeding disorder drugs (octreotide), antipsychotic (propoxyphene, phenothiazines), female sex hormones (progestogen, oestrogen), thyroid hormones (levothyroxine), anti-asthmatics (albuterol, epinephrine, terbutaline), an antidepressant (fluoxetine, lithium), lipid-lowering pills (reserpine, niacin, clonidine, fenofibrate, guanethidine), pain killers (aspirin). If you are taking any of the above, speak with your doctor.

Drug-Disease Interaction:

INSULIN HUMAN should not be given to patients with kidney disease, liver disease, low blood sugar/glucose level (hypoglycaemia), and low potassium level (hypokalaemia).

Safety Advice

ALCOHOL

You are recommended not to consume alcohol along with INSULIN HUMAN to avoid unpleasant side-effects. Alcohol may either decrease or increase the blood sugar level which can be fatal.

PREGNANCY

INSULIN HUMAN can be used during pregnancy. Your insulin dose may need to be changed during pregnancy and after delivery.

BREAST FEEDING

INSULIN HUMAN can be given safely to nursing mothers but only under the supervision of a physician.

DRIVING

Drive with caution, INSULIN HUMAN usually causes drowsiness and affects driving ability. Your ability to concentrate and react may be reduced if you have hypoglycaemia (low blood sugar).

LIVER

INSULIN HUMAN to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

KIDNEY

INSULIN HUMAN to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.