PRODUCT DETAILS

About Exinia 50 Tablet

EPLERENONE belongs to a class of medicine called 'diuretics' (water pills) primarily used to treat hypertension (high blood pressure). It also maintains the bloodstream's potassium level, removes excess water from the body, and prevents hypertension (high blood pressure) due to edema (fluid retention). Blood pressure is the measurement of the force that our heart uses to pump blood to all body parts. Hypertension is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart.

EPLERENONE contains Eplerenone, which is prescribed for the treatment of hypertension. EPLERENONE works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and reduces the heart's workload, making the heart more efficient at pumping blood throughout the body. Thus, it also helps lower high blood pressure, reducing the chances of any future heart attack, stroke, or angina (chest pain) in the future.

Take EPLERENONE as prescribed by your doctor. You are advised to take EPLERENONE for as long as your doctor has prescribed it for you, depending upon your medical condition. You may experience dehydration, electrolyte disturbances (calcium, magnesium, and sodium), constipation, itching, and increased uric acid in some cases. Most of these side effects of EPLERENONE do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking EPLERENONE of your own as doing so may raise your blood pressure, thereby increasing the risk of getting heart diseases and stroke. Inform your doctor if you have any kidney disease (with creatinine clearance less than 30 mL/min), liver disease, high serum potassium (hyperkalemia), diabetes mellitus type 2, and patients with nil urine output (anuria). If you are pregnant or breastfeeding, please tell your doctor so that the dosage of EPLERENONE can be prescribed accordingly. Please tell your doctor if you are taking any other medicines or are allergic to EPLERENONE. Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling. Please take EPLERENONE at least 4 hours before sleeping to avoid frequent urination at night. Also, do not take EPLERENONE along with lithium to avoid serious side effects. St. John's wort plant should not be taken along with EPLERENONE. 

Uses of Exinia 50 Tablet

Hypertension (high blood pressure), Edema

Medicinal Benefits of Exinia 50 Tablet

EPLERENONE is primarily used to treat hypertension (high blood pressure) and heart failure. It also treats edema (reduces swelling) caused due to other conditions. EPLERENONE works by increasing the amount of urine passing from the kidneys. It effectively reduces excess fluid levels in the body and reduces the heart's workload, and makes the heart more efficient at pumping blood throughout the body. Thus, it also helps lower high blood pressure, reducing the chances of any future heart attack, stroke, or angina (chest pain) in the future.

Directions for Use

EPLERENONE be with or without food. The tablet form of EPLERENONE should be swallowed as a whole with a glass of water, do not chew or break the tablet. It is best to avoid taking this medication within 4 hours of your bedtime to prevent having to get up to urinate.

Side Effects of Exinia 50 Tablet

Like all medicines, EPLERENONE also has some side effects. You may experience dizziness, nausea, dizziness, headache, cough, increased creatinine and potassium in the blood, and fatigue in some cases. Most of these side effects of EPLERENONE do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

EPLERENONE should not be given to the people allergic to EPLERENONE, have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease (with creatinine clearance less than 30 mL/min), liver disease, high serum potassium (hyperkalemia), diabetes mellitus type 2 and patients with nil urine output (anuria), pregnant women, planning to get pregnant and breastfeeding women. EPLERENONE can pass into breast milk, but its effect on the baby is unknown, so it is better to tell your doctor if you are taking EPLERENONE and breastfeeding. Dehydration with electrolyte and acid-base disturbances must be corrected before using EPLERENONE. Do not take any extra potassium supplements or potassium-rich foods such as bananas and broccoli with EPLERENONE. It may lead to an excessive increase in blood potassium levels (hyperkalemia). Please take EPLERENONE at least 4 hours before sleeping to avoid frequent urination at night. Also, do not take EPLERENONE along with lithium to avoid serious side effects. St. John's wort plant should not be taken along with EPLERENONE. 

Drug Interactions

Drug-Drug Interaction:

EPLERENONE may interact with other high blood pressure-lowering pills (metoprolol, ramipril, hydrochlorothiazide), and it can lower your blood pressure leading to severe conditions. Besides this, it also interacts with blood thinners (aspirin, warfarin), anti-epilepsy medicines (carbamazepine, phenobarbital), immune-suppressing drugs (cyclosporine), painkillers (ibuprofen), anti-fungal medicines (itraconazole, ketoconazole), HIV medicines (ritonavir, nelfinavir), anti-bacterial medicines (clarithromycin, telithromycin), anti-depressants (lithium).

Drug-Disease Interaction:

EPLERENONE should not be given to people with low blood pressure (hypotension), coronary heart disease, liver or kidney disease, heart failure, high serum potassium (hyperkalemia), diabetes mellitus type 2, and patients with nil urine output (anuria).

Safety Advice

ALCOHOL

You are recommended not to consume alcohol along with EPLERENONE to avoid unpleasant side effects.

PREGNANCY

EPLERENONE must not be taken during pregnancy. It is only if prescribed by a doctor and if benefits overweigh harms.

BREAST FEEDING

Breast-feeding must be avoided during treatment with EPLERENONE. It is only if prescribed by a doctor and if benefits overweigh harms.

DRIVING

It is not recommended to drive after taking EPLERENONE as it may occasionally cause drowsiness due to orthostatic hypotension (sudden drop in blood pressure on standing from lying position).

LIVER

EPLERENONE to be taken with caution, especially if you have a history of Liver diseases/conditions. Your doctor may adjust your dose depending upon your current kidney conditions.

KIDNEY

EPLERENONE to be taken with caution, especially if you have a history of Kidney diseases/conditions. Your doctor may adjust your dose depending upon your current kidney conditions.