PRODUCT DETAILS

About Montidox 400mg/10mg Tablet

DOXOFYLLINE+MONTELUKAST is a respiratory medication, primarily used to treat and prevent asthma and chronic obstructive pulmonary diseases (COPD). Asthma is a breathing problem in which airways narrow, swell and produce extra mucus, leading to difficulty breathing. COPD is a group of lung diseases that mainly include emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of your bronchial tubes).

DOXOFYLLINE+MONTELUKAST is a combination of two medicines: Doxofylline (bronchodilator) and Montelukast (leukotriene receptor antagonist). Doxofylline (also known as Doxophylline) belongs to the class of bronchodilators. It effectively treats bronchial asthma, COPD, and bronchospasm (tightening of airways’ muscles, causing difficulty breathing). It works by relaxing muscles and widening the airways of the lungs. Doxofylline treats the airflow obstruction in the lungs, thereby relieving chest tightness, wheezing, and cough to make breathing easier. Montelukast belongs to the class of leukotriene receptor antagonists. Leukotrienes are inflammatory chemicals that are released by the body when an allergen comes into contact. These chemicals cause swelling in the lungs and tightening of the airway's muscles, which are the primary causes of asthma attacks. Montelukast blocks these leukotrienes, thereby reducing inflammation and swelling in the nose. It also inhibits bronchoconstriction (narrowing of airways in the lungs that lead to breathing difficulties) and is used in treating asthma and allergic rhinitis.

DOXOFYLLINE+MONTELUKAST is available in the form of oral tablets. Your doctor will advise the dose and duration of the course based on the severity of your disease. The common side effects of DOXOFYLLINE+MONTELUKAST include fever, nausea, vomiting, stomach pain/epigastric pain, headache, insomnia (difficulty in sleeping), irritation, sore throat, increased heart rate, and flu-like symptoms. Most of these side effects of DOXOFYLLINE+MONTELUKAST do not require any medical attention and gradually resolve over time. However, if the side effects are persistent, please reach out to your doctor.

Please inform your doctor in advance if you have heart, liver, kidney, and lung diseases, neuropsychiatric disorders like seizures (fits) and depression, phenylketonuria (birth defect caused by the build-up of an amino acid called phenylalanine in the body), hyperthyroidism (overactive thyroid), high blood pressure, hypoxemia (low levels of oxygen in the blood), stomach ulcers and viral infections before taking DOXOFYLLINE+MONTELUKAST. DOXOFYLLINE+MONTELUKAST is not intended for use during an acute asthma attack. Your doctor may suggest other medications for your sudden asthma attack. 

Therapy with leukotriene receptor antagonists like Montelukast should be cautiously administered in patients with neuropsychiatric disorders. There are chances of developing psychiatric-type effects, including agitation, aggressive behavior, anxiety, depression, abnormal dreams, and hallucinations. DOXOFYLLINE+MONTELUKAST is contraindicated in lactation. It is advisable to check with your doctor if you are pregnant, currently breastfeeding, or taking any other prescribed or non-prescribed medicines before starting DOXOFYLLINE+MONTELUKAST.

Uses of Montidox 400mg/10mg Tablet

Chronic Obstructive Pulmonary Disease (COPD), Bronchitis, Asthma, Emphysema, Bronchospasm, and Allergic rhinitis.

Medicinal Benefits of Montidox 400mg/10mg Tablet

DOXOFYLLINE+MONTELUKAST is used to treat and prevent respiratory disorders like asthma attacks and chronic obstructive pulmonary diseases (COPD). DOXOFYLLINE+MONTELUKAST is a combination of Doxofylline and Montelukast. Doxofylline belongs to the bronchodilators class and is used in treating bronchial asthma, COPD, and bronchospasm (tightening of airway muscles, causing difficulty breathing). It works by relaxing muscles and widening the airways of the lungs. Doxofylline treats the airflow obstruction in the lungs, thereby relieving chest tightness, wheezing, and cough to make breathing easier. Montelukast is a leukotriene receptor antagonist. Montelukast blocks leukotrienes (chemicals released in response when a body comes in contact with an allergen) and reduces inflammation and swelling in the nose. It also inhibits bronchoconstriction (narrowing of airways in the lungs that lead to breathing difficulties) and is used to treat asthma and allergic rhinitis. Montelukast is also used to relieve exercise-induced bronchospasm (shortness of breath that occurs only during exercise).

Directions for Use

DOXOFYLLINE+MONTELUKAST is available in the form of oral tablets. Your doctor will advise the dose and duration of DOXOFYLLINE+MONTELUKAST based on the severity of your disease. Montelukast is also available in the form of chewable tablets. Doxofylline is also available in ampoules, sachets for pediatric use, and syrup formulations. Tablet: Use DOXOFYLLINE+MONTELUKAST as prescribed by your doctor. Take DOXOFYLLINE+MONTELUKAST with or without food and swallow it whole with a glass of water. Do not crush, chew or break it.

Side Effects of Montidox 400mg/10mg Tablet

• Fever
• Nausea
• Vomiting
• Stomach pain/epigastric pain
• Headache
• Insomnia (difficulty in sleeping)
• Irritation
• Sore throat
• Increased heart rate
• Flu-like symptoms

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Before taking DOXOFYLLINE+MONTELUKAST, let your doctor know if have heart, liver, kidney, and lung diseases, neuropsychiatric disorders like seizures (fits) and depression,  phenylketonuria (birth defect caused by the build-up of an amino acid called phenylalanine in the body), hyperthyroidism (overactive thyroid), high blood pressure, hypoxemia (low levels of oxygen in the blood), stomach ulcers and viral infections. DOXOFYLLINE+MONTELUKAST is not intended for use during an acute asthma attack. Do not stop taking this medicine of your own unless advised by your doctor.

Therapy with leukotriene receptor antagonists like Montelukast should be cautiously administered in patients with neuropsychiatric disorders. There are chances of developing psychiatric-type effects, including agitation, aggressive behavior, anxiety, depression, abnormal dreams, and hallucinations. Montelukast may excrete into the breast milk during breastfeeding and affect the newborn. Doxofylline is contraindicated in lactation/breastfeeding. Please seek medical advice if you are pregnant, currently breastfeeding, or taking any other prescribed or non-prescribed medicines before starting DOXOFYLLINE+MONTELUKAST.

Drug Interactions

Drug-Drug Interaction:

DOXOFYLLINE+MONTELUKAST may interact with medicines used to treat gout (allopurinol), antacid (cimetidine), antibiotics (erythromycin, lincomycin, ciprofloxacin, clindamycin,), drugs treating fits (phenytoin), asthma medicine (salbutamol) and influenza vaccine.

Drug-Disease Interaction:

DOXOFYLLINE+MONTELUKAST is contraindicated in patients with heart, liver, kidney, and lung diseases, neuropsychiatric disorders like seizures (fits) and depression, phenylketonuria (birth defect caused by the build-up of an amino acid called phenylalanine in the body), hyperthyroidism (overactive thyroid), high blood pressure, hypoxemia (low oxygen levels in the blood), stomach ulcers and viral infections.

Safety Advice

ALCOHOL

Avoid drinking alcohol while taking this medicine as it can worsen your side effects like drowsiness

PREGNANCY

There is limited data on how DOXOFYLLINE+MONTELUKAST affects pregnancy. Please consult your doctor if you are planning to conceive or are already pregnant before starting DOXOFYLLINE+MONTELUKAST.

BREAST FEEDING

There is limited data on how DOXOFYLLINE+MONTELUKAST affects breastfeeding. However, Doxofylline is contraindicated in breastfeeding, and Montelukast may pass into breast milk. Please consult your doctor before starting DOXOFYLLINE+MONTELUKAST.

DRIVING

Do not drive or operate machinery if you experience drowsiness or difficulty concentrating while using DOXOFYLLINE+MONTELUKAST. DOXOFYLLINE+MONTELUKAST may affect your ability to drive. Seek medical attention if the symptoms persist longer.

LIVER

DOXOFYLLINE+MONTELUKAST should be used with caution in patients with liver diseases. Let your doctor know if you have any history of hepatic impairment caused by alcohol use or cirrhosis or any other form of liver disease, since it may cause decreased metabolism of Montelukast. DOXOFYLLINE+MONTELUKAST may also cause liver enzyme changes. Your doctor will weigh the benefits and potential risks before prescribing DOXOFYLLINE+MONTELUKAST.

KIDNEY

DOXOFYLLINE+MONTELUKAST should be used with caution in patients with kidney diseases. Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing DOXOFYLLINE+MONTELUKAST.